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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKZ
All Species:
12.73
Human Site:
Y508
Identified Species:
21.54
UniProt:
Q13574
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13574
NP_001099010.1
1117
124128
Y508
I
I
Q
S
F
L
W
Y
L
N
P
R
Q
V
F
Chimpanzee
Pan troglodytes
XP_508395
1117
124129
Y508
I
I
Q
S
F
L
W
Y
L
N
P
R
Q
V
F
Rhesus Macaque
Macaca mulatta
XP_001102461
1084
120447
Y475
I
I
Q
S
F
L
W
Y
L
N
P
R
Q
V
F
Dog
Lupus familis
XP_540755
766
85714
E234
F
M
L
Q
Q
I
E
E
P
C
S
L
G
V
H
Cat
Felis silvestris
Mouse
Mus musculus
Q80UP3
929
104029
Y397
T
L
N
W
G
G
G
Y
T
D
E
P
V
S
K
Rat
Rattus norvegicus
O08560
929
103991
Y397
T
L
N
W
G
G
G
Y
T
D
E
P
V
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513139
955
107141
S423
V
T
L
E
F
H
E
S
R
E
A
N
P
E
K
Chicken
Gallus gallus
NP_001026363
953
106222
I421
S
H
V
E
D
G
N
I
V
Q
L
D
R
W
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922445
1086
121319
K492
D
R
W
N
L
V
V
K
P
N
P
E
A
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09103
1457
160124
L836
L
L
G
K
F
Q
H
L
L
N
P
R
Q
V
F
Honey Bee
Apis mellifera
XP_396522
837
92900
D305
E
S
E
T
V
L
L
D
R
W
Q
L
V
V
E
Nematode Worm
Caenorhab. elegans
Q10024
937
105180
V405
K
S
H
R
Q
F
V
V
K
P
T
D
L
W
S
Sea Urchin
Strong. purpuratus
XP_796061
815
92455
S283
Q
R
K
K
K
K
P
S
I
K
R
K
S
I
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
V196
C
L
W
C
Q
R
L
V
H
V
D
C
H
S
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
90.3
65.1
N.A.
78.2
79.3
N.A.
54.7
67.8
N.A.
60.4
N.A.
31.9
31.2
31.6
43.1
Protein Similarity:
100
99.8
91.2
66.6
N.A.
80.5
80.5
N.A.
65.8
74.8
N.A.
70.6
N.A.
46.1
46.2
46.3
55
P-Site Identity:
100
100
100
6.6
N.A.
6.6
6.6
N.A.
6.6
0
N.A.
13.3
N.A.
53.3
13.3
0
0
P-Site Similarity:
100
100
100
20
N.A.
20
20
N.A.
13.3
13.3
N.A.
26.6
N.A.
66.6
26.6
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% A
% Cys:
8
0
0
8
0
0
0
0
0
8
0
8
0
0
0
% C
% Asp:
8
0
0
0
8
0
0
8
0
15
8
15
0
0
0
% D
% Glu:
8
0
8
15
0
0
15
8
0
8
15
8
0
8
8
% E
% Phe:
8
0
0
0
36
8
0
0
0
0
0
0
0
0
29
% F
% Gly:
0
0
8
0
15
22
15
0
0
0
0
0
8
8
0
% G
% His:
0
8
8
0
0
8
8
0
8
0
0
0
8
0
8
% H
% Ile:
22
22
0
0
0
8
0
8
8
0
0
0
0
8
0
% I
% Lys:
8
0
8
15
8
8
0
8
8
8
0
8
0
0
22
% K
% Leu:
8
29
15
0
8
29
15
8
29
0
8
15
8
0
0
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
15
8
0
0
8
0
0
36
0
8
0
0
15
% N
% Pro:
0
0
0
0
0
0
8
0
15
8
36
15
8
0
8
% P
% Gln:
8
0
22
8
22
8
0
0
0
8
8
0
29
0
0
% Q
% Arg:
0
15
0
8
0
8
0
0
15
0
8
29
8
0
0
% R
% Ser:
8
15
0
22
0
0
0
15
0
0
8
0
8
22
15
% S
% Thr:
15
8
0
8
0
0
0
0
15
0
8
0
0
0
0
% T
% Val:
8
0
8
0
8
8
15
15
8
8
0
0
22
43
0
% V
% Trp:
0
0
15
15
0
0
22
0
0
8
0
0
0
15
0
% W
% Tyr:
0
0
0
0
0
0
0
36
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _